Enzyme- and metal-free electrochemical sensor for highly sensitive superoxide anion detection based on nitrogen doped hollow mesoporous carbon spheres

摘要

In this work, a highly sensitive enzyme- and metal-free electrochemical method for superoxide anion (O[rad]) detection has been developed by employing screen-printed carbon electrodes (SPCE) modified by nitrogen doped hollow mesoporous carbon spheres (N-HMCS). For comparison, solid carbon spheres (SCS) and hollow mesoporous carbon spheres (HMCS) were also synthesized to fabricate the modified SPCE. Compared with SCS/SPCE and HMCS/SPCE, N-HMCS/SPCE displayed a higher electrochemical performance. When applied for electrochemical detection of O[rad], N-HMCS/SPCE exhibited a high sensitivity of 1.49 μA cm μM, better than SCS/SPCE and HMCS/SPCE and many of enzyme- or metal-based superoxide anion sensors. N-HMCS is expected to become a new generation of sensing materials for electrochemical analysis of O[rad].